Wegovy (semaglutide) should be stored in the refrigerator between 36°F and 46°F (2°C to 8°C). Unopened Wegovy pens can last until the expiration date printed on the packaging, typically up to 30 days after purchase if stored properly. Once you have opened the pen for use, it remains effective for up to 28 days when kept in the refrigerator. After 28 days, the medication may lose its potency, even if it still appears to be intact.

Factors That Affect Wegovy's Shelf Life

The shelf life of Wegovy can be influenced by several factors:

• Temperature: Storing Wegovy at temperatures higher or lower than the recommended range (36°F to 46°F) can decrease its effectiveness. Freezing or excessive heat can cause it to lose potency.
• Exposure to Light: Wegovy should be kept in its original packaging to protect it from light. Extended exposure to light can damage the medication and reduce its shelf life.
• Pen Condition: If the Wegovy pen is damaged or shows signs of leaking, it may not work properly, which can also shorten its shelf life. Always inspect the pen before use.
• Storage Time: Unopened Wegovy pens can last until their printed expiration date if stored correctly. However, opened pens are only effective for up to 28 days.

Proper Way to Store Wegovy in the Refrigerator

To store Wegovy properly in the fridge, follow these steps:

• Keep It in the Original Packaging: This protects the medication from light and helps maintain its integrity.
• Avoid Freezing: Wegovy should never be frozen. Freezing the pen can damage the medication and make it ineffective. If you accidentally freeze it, discard the pen.
• Refrigerator Placement: Store the pen in a part of the fridge where the temperature remains stable. Avoid placing it in the door or areas prone to temperature fluctuations.
• After Opening: Once opened, Wegovy should remain in the fridge and be used within 28 days. If it hasn’t been used within that time frame, it should be discarded.

Signs That Wegovy Has Expired or Is No Longer Effective

Wegovy may lose its potency over time or after improper storage. Here are signs that it may no longer be effective:

• Changes in Appearance: If the solution inside the pen appears discolored, cloudy, or contains visible particles, it may have expired or been damaged. Wegovy should be clear and colorless.
• Expiration Date: Always check the expiration date on the pen. If it has passed, the medication should not be used.
• Smell: If the medication has a strange or unusual odor, it may no longer be safe or effective.
• Leakage or Damage: If the pen is leaking or appears damaged, do not use it. A damaged pen could result in incorrect dosing.

How to Safely Dispose of Expired Wegovy

Proper disposal of expired Wegovy is essential to avoid potential harm. Here’s how to dispose of it:

• Do Not Flush or Throw in Trash: Do not dispose of Wegovy by flushing it down the toilet or throwing it in the regular trash, as it can harm the environment.
• Use a Drug Take-Back Program: The best way to dispose of expired medications, including Wegovy, is through a drug take-back program. Many pharmacies and community centers offer this service.
• Needle Disposal: If you have used needles or syringes, dispose of them in a proper sharps container. These are available at pharmacies or health clinics.

Can Wegovy Be Stored at Room Temperature?

Wegovy should ideally be stored in the refrigerator, but it can be stored at room temperature (up to 86°F or 30°C) for a short period. If you need to travel or have temporarily lost refrigeration, Wegovy can be kept at room temperature for up to 28 days. After this time, any remaining medication should be discarded, even if it looks fine. If Wegovy exceeds the 28-day window at room temperature, it may lose effectiveness, and using it could be unsafe. Always try to store it in a cool, stable environment to ensure the best results.